Protein Disorder Prediction/Predictor 1.3

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SwissProt ID or AC:

(e.g. PRIO_HUMAN or P09429)

Sequence (Amino acid single letter IUPAC code):

Algorithm Parameters:

Savitzky-Golay smoothing frame
Minimum peak width
Maximum join distance

Stringency values for different predictors:

Coils threshold
Remark465 threshold
Hot loops threshold

Plot Settings:

Use Java applet for displaying results
Invert background colour
Integrate curves (GlobPlot like graphs)

Prediction of low-complexity regions:


Prediction of cross-beta aggregation (relevant for amyloidosis):

Run Tango
(Under development - SLOW - only for less than 250 residues)

Temperature (Kelvin)
Ionic Strength (M)
TFE concentration (M)
Tango threshold


R. Linding, L.J. Jensen, F. Diella, P. Bork, T.J. Gibson and R.B. Russell
Protein disorder prediction: implications for structural proteomics
Structure Vol 11, Issue 11, 4 November 2003

Please see the DisEMBL preview paper as well.

Tango is developed by Luis Serrano at EMBL, please refer to Tango's website for further information.

Remember to submit your sequence to GlobPlot as well.